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G3796

Sigma-Aldrich

Granisetron hydrochloride

≥98% (HPLC), solid

Synonym(s):

1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride

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50 MG
₹10,340.00

About This Item

Empirical Formula (Hill Notation):
C18H24N4O· HCl
CAS Number:
Molecular Weight:
348.87
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

₹10,340.00


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Quality Level

Assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to off-white

mp

284.0-290.0 °C

solubility

H2O: >10 mg/mL

originator

Roche

storage temp.

room temp

SMILES string

Cl.CN1[C@H]2CCC[C@@H]1C[C@@H](C2)NC(=O)c3nn(C)c4ccccc34

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1 of 4

This Item
W276200W263508W263516
Ocimene mixture of isomers, stabilized, ≥90%

W353901

Ocimene

Myrcene stabilized, FCC, FG

W276200

Myrcene

Linalool ≥97%, FCC, FG

W263508

Linalool

organoleptic

green; woody; tropical

organoleptic

green; spicy; woody; balsamic; vegetable

organoleptic

lemon; orange; floral; sweet

organoleptic

woody; floral

biological source

synthetic

biological source

synthetic

biological source

synthetic

biological source

-

agency

meets purity specifications of JECFA

agency

follows IFRA guidelines, meets purity specifications of JECFA

agency

follows IFRA guidelines, meets purity specifications of JECFA

agency

follows IFRA guidelines

assay

≥90%

assay

-

assay

≥97%

assay

≥95%

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

refractive index

n20/D 1.485

refractive index

n20/D 1.469 (lit.)

refractive index

n20/D 1.462 (lit.)

refractive index

n20/D 1.4615 (lit.)

Biochem/physiol Actions

Granisetron hydrochloride helps to block nausea/emesis and abdominal pain in irritable bowel syndrome, that is stimulated by chemotherapy.[1]
Granisetron hydrochloride is a serotonin 5-HT3 receptor antagonist and antiemetic.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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