L5918

Lomustine

≥98%

• Synonym(s): 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
• Empirical Formula (Hill Notation): C₉H₁₆ClN₃O₂
• CAS Number: 13010-47-4
• Molecular Weight: 233.70
• EC Number: 235-859-2
• MDL number: MFCD00012392
• UNSPSC Code: 12352100
• PubChem Substance ID: 329817632
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥98%
• storage temp.: −20°C
• SMILES string: ClCCN(N=O)C(=O)NC1CCCCC1
• InChI: 1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
• InChI key: GQYIWUVLTXOXAJ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301,H350
• Precautionary Statements: P201 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves