L9125

L-Leucine-p-nitroanilide

leucine aminopeptidase substrate, chromogenic, ≥98% (TLC), powder

• Synonym(s): L-Leucine-4-nitroanilide
• Empirical Formula (Hill Notation): C₁₂H₁₇N₃O₃
• CAS Number: 4178-93-2
• Molecular Weight: 251.28
• Beilstein: 2218433
• EC Number: 224-047-3
• MDL number: MFCD00063681
• UNSPSC Code: 12352204
• PubChem Substance ID: 24896516
• NACRES: NA.32

Properties

• Product Name: L-Leucine-p-nitroanilide, leucine aminopeptidase substrate
• Quality Level: 200
• Assay: ≥98% (TLC)
• form: powder
• solubility: ethanol: 50 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC(C)C[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1
• InChI key: AXZJHDNQDSVIDR-NSHDSACASA-N

Description

Application

L-Leucine-p-nitroanilide has been used as substrate

• for the determination of intestinal leucine aminopeptidase activity of juvenile rainbow trout (Oncorhynchus mykiss)
• in insulin-regulated aminopeptidase inhibition assay
• for determining exopeptidase activity

Substrates

Substrate for the colorimetric determination of leucine aminopeptidase.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317,H319
• Precautionary Statements: P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves