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Key Documents

M0317

Sigma-Aldrich

Microsomes from Liver, Pooled

from human

Synonym(s):

Liver Microsomes

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About This Item

UNSPSC Code:
12161501
NACRES:
NA.47

biological source

human

Quality Level

packaging

vial of ~10 mg

shipped in

dry ice

storage temp.

−70°C

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Application

Microsomes from liver have been used to study the in vitro effect of Clinacanthus nutans leaves on the activity of cytochrome P450 3A4 and 2E1.

Biochem/physiol Actions

Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.
Source of drug metabolizing enzymes, including cytochrome P-450.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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