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Key Documents

M3064

Sigma-Aldrich

Myostatin human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

GDF-8, Growth Differentiation Factor - 8

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77

biological source

human

Quality Level

recombinant

expressed in E. coli

Assay

≥95% (SDS-PAGE)

form

lyophilized powder

mol wt

16 kDa (including a 31 amino-acid spacer and 6-His tag)

packaging

pkg of 0.1 mg

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... MSTN(2660)

Application

Use recombinant myostatin to study its mechanisms of action in vitro.

Biochem/physiol Actions

Myostatin is a 25 KDa, homodimer, that acts on muscle to induce SMAD family transcription factors such as SMAD2 and SMAD3. It inhibits the differentiation of myoblasts into mature muscle fibers. Positive control for myostatin in Western blots and ELISA.
Positive control for myostatin in Western blots and ELISA.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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