M4414

Myristoyl coenzyme A lithium salt

≥80.0% (HPLC), powder, protein myristoylation substrate

• Synonym(s): n-Tetradecanoyl Coenzyme A lithium salt
• Empirical Formula (Hill Notation): C₃₅H₆₂N₇O₁₇P₃S · xLi⁺
• CAS Number: 187100-75-0
• Molecular Weight: 977.89 (free acid basis)
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• Product Name: Myristoyl coenzyme A lithium salt, ≥80.0%
• Quality Level: 200
• Assay: ≥80.0%
• storage temp.: −20°C

Description

Biochem/physiol Actions

Myristoyl coenzyme A is a combination of coenzyme A and myristate. It serves as a substrate in protein myristoylation, catalyzed by the enzyme N-myristoyl transferase. Myristyolation involves the transfer of the myristoyl group to the glycine residue at the amino-terminal of the protein.

Features and Benefits

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Substrates

Long chain fatty acid (C14) covalently linked to Coenzyme A. Substrate for de novo fatty acid synthesis. Fatty acylation has been shown to block G protein-associated calcium release by a direct allosteric modification of a component of the GTP-activated process.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves