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Key Documents

M4603

Sigma-Aldrich

Acetyl-[Nle4, Asp5, D-2-Nal7, Lys10]-cyclo-α-Melanocyte Stimulating Hormone Amide Fragment 4-10

≥95% (HPLC)

Synonym(s):

SHU9119

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About This Item

Empirical Formula (Hill Notation):
C54H71N15O9
Molecular Weight:
1074.24
MDL number:
MFCD02093607
UNSPSC Code:
51111800
NACRES:
NA.32

Quality Level

200

Assay

≥95% (HPLC)

UniProt accession no.

P01189

storage temp.

−20°C

Gene Information

human ... POMC(5443)

Related Categories

Amino Acid Sequence

Ac-Nle-cyclo(Asp-His-Nal-Arg-Trp-Lys-NH2)

Biochem/physiol Actions

Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. This compound shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBS0887V
BCBH6799V
1403981
063K1005
117K1106

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