M6751

5-Methylcytosine hydrochloride

≥99%

• Synonym(s): 4-Amino-2-hydroxy-5-methylpyrimidine
• Empirical Formula (Hill Notation): C₅H₇N₃O · HCl
• CAS Number: 58366-64-6
• Molecular Weight: 161.59
• EC Number: 261-223-9
• MDL number: MFCD11053426
• UNSPSC Code: 41106305
• PubChem Substance ID: 24897110
• NACRES: NA.51

Properties

• biological source: synthetic (organic)
• Quality Level: 200; 300
• Assay: ≥99%
• form: crystalline powder
• solubility: water: 50 mg/mL, clear to slightly hazy, colorless
• SMILES string: O=C1NC(N)=C(C)C=N1.[H]Cl
• InChI: 1S/C5H7N3O.ClH/c1-3-2-7-5(9)8-4(3)6;/h2H,1H3,(H3,6,7,8,9);1H
• InChI key: ANWMULVRPAUPJT-UHFFFAOYSA-N

Description

Application

5-Methylcytosine hydrochloride has been used as standard in high performance liquid chromatography (HPLC) for the estimation of global methylation rates. It has also been used in high-resolution mass spectroscopic analysis.

5-Methylcytosine is used in studies of DNA methylation processes (epigenetics).

Biochem/physiol Actions

5-Methylcytosine mediates gene expression, genomic imprinting and inhibition of transposable elements. It is closely associated with translational fidelity and tRNA recognition.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves