N2288

Nefiracetam

solid

• Synonym(s): (2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide), DM-9384
• Empirical Formula (Hill Notation): C₁₄H₁₈N₂O₂
• CAS Number: 77191-36-7
• Molecular Weight: 246.30
• MDL number: MFCD00209882
• UNSPSC Code: 12352200
• PubChem Substance ID: 329818410
• NACRES: NA.77

Properties

• form: solid
• Quality Level: 100
• color: white to off-white
• solubility: DMSO: >5 mg/mL
• SMILES string: Cc1cccc(C)c1NC(=O)CN2CCCC2=O
• InChI: 1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17)
• InChI key: NGHTXZCKLWZPGK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Nefiracetam (NEF) is a pyrrolidonetype nootropic agent with various pharmacologic as well as cognition enhancing effects. In amygdala-kindled seizures, nefiracetam inhibits both electroencephalographic and behavioral seizures. NEF has a distinct anticonvulsant spectrum.

Novel pyrrolidonetype nootropic (condition enhancing) agent with anticonvulsant spectrum.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves