N3385

N-Nitroso-N-ethylurea

ISOPAC^®

• Synonym(s): ENU, N-Ethyl-N-nitrosourea
• Empirical Formula (Hill Notation): C₃H₇N₃O₂
• CAS Number: 759-73-9
• Molecular Weight: 117.11
• EC Number: 212-072-2
• MDL number: MFCD00053635
• UNSPSC Code: 12352102
• PubChem Substance ID: 24897640
• NACRES: NA.25

Properties

• Quality Level: 100
• form: powder
• storage temp.: −20°C
• SMILES string: CCN(N=O)C(N)=O
• InChI: 1S/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7)
• InChI key: FUSGACRLAFQQRL-UHFFFAOYSA-N

Description

Application

N-Nitroso-N-ethylurea has been used as a mutation-inducing agent.

Biochem/physiol Actions

DNA alkylating agent that is carcinogenic in many animal species. Induces benign and malignant tumors of numerous types, including the nervous tissue, stomach, esophagus, pancreas, respiratory tract, intestine, lymphoreticular tissues, skin, and kidney.

Packaging

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.
1 vial contains 1 g of material calculated on anhydrous basis.

Caution

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301,H312 + H332,H350,H360
• Precautionary Statements: P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves