N3905

Nicarbazin

• Synonym(s): N,N′-bis(4-Nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone
• Empirical Formula (Hill Notation): C₁₃H₁₀N₄O₅ · C₆H₈N₂O
• CAS Number: 330-95-0
• Molecular Weight: 426.38
• EC Number: 206-359-1
• MDL number: MFCD00867204
• UNSPSC Code: 51102829
• PubChem Substance ID: 329818641
• NACRES: NA.85

Properties

• form: powder
• Quality Level: 100
• antibiotic activity spectrum: parasites
• Mode of action: cell membrane | interferes
• SMILES string: Cc1cc(C)nc(O)n1.[O-][N+](=O)c2ccc(NC(=O)Nc3ccc(cc3)[N+]([O-])=O)cc2
• InChI: 1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9)
• InChI key: UKHWDRMMMYWSFL-UHFFFAOYSA-N

Description

Application

Nicarbazin is a coccidiostat (antiprotozoal agent) in the poultry industry and is a contraceptive for resident Canada geese and waterfowl. It is used to study avian reproduction and is used to interfere with the formation of the vitelline (yolk) membrane in bird eggs. It has been used to study how delivery method can effect plasma levels of 4,4′-dinitrocarbanilide (DNC), which is the active anticoccidial component of Nicarbazin.

Biochem/physiol Actions

Nicarbazin affects avian reproduction by reducing egg production, egg weight, and egg hatchability. The mechanism of action of Nicarbazin is unknown.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves