O5507

Linoleic acid, conjugated

• Synonym(s): CLA, Octadecadienoic acid, conjugated
• UNSPSC Code: 12352211
• NACRES: NA.77

Properties

• impurities: ≤1% Linoleic acid
• Quality Level: 100
• lipid type: omega FAs
• storage temp.: −20°C

Description

General description

A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acids. Isomer ratio may vary from lot to lot.

Application

• A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis.: The paper discusses the development of a targeted nanomodulator, including conjugated linoleic acid, to manipulate the tumor microenvironment and inhibit metastasis. The findings suggest significant potential for improved cancer treatments (Tian et al., 2022).


• Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.: The research focuses on hyaluronic acid-modified nanoparticles using linoleic acid-conjugated chitosan for the codelivery of miR34a and doxorubicin. This approach aims to overcome drug resistance in breast cancer treatments (Yang et al., 2022).

Biochem/physiol Actions

Potent inhibitor of breast, skin, and colon carcinogenesis and tumor cell proliferation; inhibits bFGF-induced endothelial cell proliferation; potent antioxidant.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves