P5084

PTIO

• Synonym(s): 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide
• Empirical Formula (Hill Notation): C₁₃H₁₇N₂O₂
• CAS Number: 18390-00-6
• Molecular Weight: 233.29
• MDL number: MFCD00059929
• UNSPSC Code: 12352200
• PubChem Substance ID: 329820215
• NACRES: NA.32

Properties

• form: powder
• Quality Level: 200
• storage temp.: 2-8°C
• SMILES string: CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C
• InChI: 1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
• InChI key: DYUUGILMVYJEHY-UHFFFAOYSA-N

Description

Application

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.

Biochem/physiol Actions

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIOs) derivatives react with nitric oxide (NO) to yield the corresponding imino nitroxides (PTIs) and nitrogen dioxide (NO2).

A stable radical scavenger for nitric oxide; affects NO without affecting NO synthase; has significant inhibitory activity against NO biological actions.

Stable radical scavenger for nitric oxide without affecting NO synthase; inhibits NO activity.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves