P5394

L-α-Phosphatidylcholine

from dried egg yolk, Type X-E, ≥40% (enzymatic)

• Synonym(s): 1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC
• CAS Number: 8002-43-5
• Beilstein: 5209585
• EC Number: 232-307-2
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• biological source: egg yolk (dried)
• Quality Level: 200
• type: Type X-E
• form: solid
• concentration: ≥40% (enzymatic)
• functional group: phospholipid
• lipid type: phosphoglycerides
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
• InChI key: JLPULHDHAOZNQI-ZTIMHPMXSA-N

Description

Application

• Hydroxyzine- and cetirizine-loaded liposomes: effect of duration of thin film hydration, freeze-thawing, and changing buffer pH on encapsulation and stability.: Discusses the encapsulation efficiency of hydroxyzine and cetirizine in L-α-Phosphatidylcholine liposomes, emphasizing the impact of preparation conditions on liposomal stability and drug release (Elzainy et al., 2005).

Biochem/physiol Actions

A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves