P6905

Polythymidylic acid sodium salt

homopolymer

• Synonym(s): Poly(dT)
• CAS Number: 85597-60-0
• MDL number: MFCD00132065
• UNSPSC Code: 41106305
• NACRES: NA.51

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• form: powder
• storage temp.: −20°C

Description

Application

Polythymidylicacid sodium salt has been used as a control to compare with poly(A) in aforce-extension experiment to investigate differences in mechanical properties. Polythymidylic acid (Poly(dT)) may be used to study the characteristics of single-stranded DNA binding proteins.

Biochem/physiol Actions

Polythymidylicacid, also known as poly-deoxythymidine (poly-dT), has various applications inmolecular biology research. One of its most common uses is for mRNApurification, where it is utilized to isolate mRNA from a mixture of RNAmolecules for the preparation of cDNA libraries. In addition, poly-dT can beused as a tool for the detection of microbial contamination in water samples.It can also be used for the purification of mRNA-protein fusion molecules inmRNA Display selections.

Unit Definition

One unit will yield an A₂₆₀ of 1.0 in 1.0 ml of water (1 cm light path).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves