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P6905

Sigma-Aldrich

Polythymidylic acid sodium salt

homopolymer

Synonym(s):

Poly(dT)

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0.05 MG
MYR 371.00

MYR 371.00


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0.05 MG
MYR 371.00

About This Item

CAS Number:
MDL number:
UNSPSC Code:
41106305
NACRES:
NA.51

MYR 371.00


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biological source

synthetic (organic)

Quality Level

form

powder

storage temp.

−20°C

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Application

Polythymidylicacid sodium salt has been used as a control to compare with poly(A) in aforce-extension experiment to investigate differences in mechanical properties.[1] Polythymidylic acid (Poly(dT)) may be used to study the characteristics of single-stranded DNA binding proteins.

Biochem/physiol Actions

Polythymidylicacid, also known as poly-deoxythymidine (poly-dT), has various applications inmolecular biology research. One of its most common uses is for mRNApurification, where it is utilized to isolate mRNA from a mixture of RNAmolecules for the preparation of cDNA libraries. In addition, poly-dT can beused as a tool for the detection of microbial contamination in water samples.It can also be used for the purification of mRNA-protein fusion molecules inmRNA Display selections.[2]

Unit Definition

One unit will yield an A260 of 1.0 in 1.0 ml of water (1 cm light path).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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