P7943

L-α-Phosphatidylethanolamine from egg yolk

Type III, ≥97% (TLC), lyophilized powder

• Synonym(s): 1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin
• CAS Number: 39382-08-6
• EC Number: 254-438-4
• MDL number: MFCD00146357
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• biological source: egg yolk
• Quality Level: 200
• type: Type III
• Assay: ≥97% (TLC)
• form: lyophilized powder
• functional group: phospholipid
• lipid type: phosphoglycerides
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [P](=O)(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)(OCCN)O
• InChI: 1S/C40H80NO8P/c1-3-5-7-9-11-13-15-17-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41)36-46-39(42)32-30-28-26-24-22-16-14-12-10-8-6-4-2/h38H,3-37,41H2,1-2H3,(H,44,45)/t38-/m1/s1
• InChI key: NJGIRBISCGPRPF-KXQOOQHDSA-N

Description

General description

L-α-Phosphatidylethanolamine from egg yolk has high unsaturated fatty acid content and elicits radical-scavenging activity. L-α-Phosphatidylethanolamine (PE) is a membrane phospholipid and is interconverted to phosphotidylserine in the presence of phosphatidylserine synthase 2. PE is essential for maintaining the structural integrity of membranes. It is the second most abundant phospholipid in animals, plants and yeast and the major lipid in bacteria. It is synthesized in mitochondria in mammals.

Application

L-α-Phosphatidylethanolamine from egg yolk has been used:

• as a component of lipid mixture for the synthesis of giant unilamellar vesicles (GUVs)
• in ceramide phosphoethanolamine (CPE) synthase assay using crude sphingomyelin synthase-related protein from Hela cells
• for the standard curve generation for the quantification of lipids in plantaris muscle homogenates from mice

Packaging

Packaged under Argon.

Caution

Purity when prepared is 97-99%. Solutions exposed to room temperature can decompose 0.3-0.5% per day.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves