P9122
Anti-Purinergic Receptor P2X7 (extracellular) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-P2Z
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About This Item
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, rat, mouse
technique(s)
western blot: 1:200 using rat brain lysate and human cell lines
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... P2RX7(5027)
mouse ... P2rx7(18439)
rat ... P2rx7(29665)
General description
P2X receptors are membrane-bound ion channels that are activated by extracellular ATP. These receptors consist of seven known isoforms ranging from P2X1 to P2X7 . P2X7 modulates several cellular functions such as cell death, cytokine release and mRNA synthesis . Anti-Purinergic Receptor P2(X7) (extracellular) antibody is specific for P2X7 in rats and mice. The antibody also reacts with human K562 (Chronic myelogeneous leukemia); WEHI-231 (Lymphoma, B lymphocyte) and HL-60 (promyelocytic leukemia) cell lines.
Immunogen
Synthetic peptide corresponding to residues 136-152 of mouse P2X7 receptor. This antigenic epitope is identical in humans and rats; whereas in bovines, only 14/17 residues are identical.
Application
Anti-Purinergic Receptor P2(X7) (extracellular) antibody is suitable for use in immunoblot and western blot (1:200, using rat brain lysate and human cell lines).
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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