PZ0150

SU5614

≥98% (HPLC)

• Synonym(s): (3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
• Empirical Formula (Hill Notation): C₁₅H₁₃ClN₂O
• CAS Number: 1055412-47-9
• Molecular Weight: 272.73
• MDL number: MFCD08443928
• UNSPSC Code: 51111800
• PubChem Substance ID: 329823735
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: orange
• solubility: DMSO: ≥20 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cc1cc(C)c(\C=C2/C(=O)Nc3ccc(Cl)cc23)[nH]1
• InChI: 1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-
• InChI key: XLBQNZICMYZIQT-GHXNOFRVSA-N

Description

Biochem/physiol Actions

SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor.

SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor; selective inhibitor of VEGF and PDGF receptor tyrosine kinases.

Features and Benefits

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Hazard Statements: H413
• Precautionary Statements: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable