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Merck

SAB2109084

Sigma-Aldrich

Anti-Usp21 (N-terminal) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

ESTM28, Usp16, Usp23, W53272

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

62 kDa

species reactivity (predicted by homology)

horse, mouse, canine, rabbit, human, bovine, guinea pig, rat

concentration

0.5 mg/mL

technique(s)

western blot: 1 μg/mL

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... USP21(27005)

General description

Usp21 deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at ′Lys-4′, resulting in regulation of transcriptional initiation. Usp21 regulates gene expression via histone H2A deubiquitination. It is also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.

Immunogen

Synthetic peptide directed towards the N-terminal region of Mouse Usp21

Sequence

Synthetic peptide located within the following region: PLPPRPGPPDERLKKLELGRGRTSGSRPRGPLRADHGVPLPGSPPPAVAL

Physical form

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable



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