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Key Documents

SCP0159

Sigma-Aldrich

Granzyme B Substrate / Caspase 3 Processing Enzyme Substrate / Caspase 8 Processing Enzyme Substrate

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About This Item

Empirical Formula (Hill Notation):
C33H42N6O13
Molecular Weight:
730.72
UNSPSC Code:
12352204
NACRES:
NA.32

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥85%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Z-Ile-Glu-Thr-Asp-pNA

Application

Caspase 8 Processing Enzyme Substrate (Z-Ile-Glu-Thr-Asp-pNA; zIETD-pNa) is used as a substrate to identify, differentiate and characterize Granzyme B, Caspase 3 Processing Enzyme(s) and Caspase 8 Processing enzyme(s). Z-Ile-Glu-Thr-Asp-pNA is closely related to Z-Ile-Glu-Thr-Asp-fluoromethylketone (zIETD-fmk), an inhibitor of Caspase 8.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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