SML1023

Flucloxacillin sodium

≥95% (HPLC)

• Synonym(s): (2S,5R,6R)-6-[[[3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium, BRL 2039 sodium, FK 900 sodium, Floxacillin sodium
• Empirical Formula (Hill Notation): C₁₉H₁₆ClFN₃O₅S · Na
• CAS Number: 1847-24-1
• Molecular Weight: 475.85
• EC Number: 217-428-0
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• form: powder
• storage condition: protect from light
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: −20°C
• SMILES string: [Na+].Fc1c(c(ccc1)Cl)c2n[o]c(c2\C(=N\[C@H]3[C@H]4SC([C@@H](N4C3=O)C(=O)O)(C)C)\[O-])C
• InChI: 1S/C19H17ClFN3O5S.Na/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);/q;+1/p-1/t13-,14+,17-;/m1./s1
• InChI key: OTEANHMVDHZOPB-SLINCCQESA-M

Description

General description

Flucloxacillin sodium, a sodium salt of flucloxacillin, is a member of the penicillin class.

Application

Flucloxacillin sodium has been used as a β-lactam antibiotic to study its effects on methicillin-resistant Staphylococcus aureus (MRSA) ΔfloA mutant.

Biochem/physiol Actions

Flucloxacillin exhibits antimicrobial property.

Flucloxacillin is a narrow-spectrum β-lactam antibiotic used to treat Gram-positive bacterial infections. Flucloxacillin induces cholestatic liver damage.

Flucloxacillin is a narrow-spectrum β-lactam antibiotic.

Other Notes

Light sensitive

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable