SML1620
NGI-1
≥95% (HPLC)
Synonym(s):
5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)-benzamide, ML414
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About This Item
Empirical Formula (Hill Notation):
C17H22N4O3S2
CAS Number:
Molecular Weight:
394.51
UNSPSC Code:
12352200
NACRES:
NA.77
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Quality Level
Assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
[S](=O)(=O)(N(C)C)c1cc(c(cc1)N3CCCC3)C(=O)Nc2[s]c(cn2)C
InChI key
QPKGRLIYJGBKJL-UHFFFAOYSA-N
Related Categories
Biochem/physiol Actions
NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation.
NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation. NGI-1 inhibits the oligosaccharyltransferase, preventing the attachment to the protein. NGI-1 has been shown to induce senescence in receptor tyrosine kinase dependent tumors.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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