SML2025

AH-7614

≥98% (HPLC)

• Synonym(s): 4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide, AH 7614, Compound 39, NSC 31171, p-Toluenesulfonamide, N-xanthen-9-yl-
• Empirical Formula (Hill Notation): C₂₀H₁₇NO₃S
• CAS Number: 6326-06-3
• Molecular Weight: 351.42
• MDL number: MFCD00379273
• UNSPSC Code: 41121800
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=S(NC1C2=C(C=CC=C2)OC3=C1C=CC=C3)(C4=CC=C(C)C=C4)=O
• InChI: 1S/C20H17NO3S/c1-14-10-12-15(13-11-14)25(22,23)21-20-16-6-2-4-8-18(16)24-19-9-5-3-7-17(19)20/h2-13,20-21H,1H3
• InChI key: OZCQEUZTOAAWDK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

AH-7614 is a potent negative allosteric modulator (NAM) of the long-chain free fatty acid receptor FFA4 that prevents differentiation of a mouse mesenchymal stem cell line toward an adipocyte phenotype. AH-7614 (Compound 39) was first described as antagonist of FFA4 that blocks activation of FFA4 by polyunsaturated, ω-6 fatty acid, linoleic acid and GSK137647A.

Potent negative allosteric modulator (NAM) of the long-chain free fatty acid receptor FFA4

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable