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SML2377

Sigma-Aldrich

GSK′962

≥98% (HPLC)

Synonym(s):

1-[(5R)-4,5-Dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-1-propanone; 2,2-Dimethyl-1-(5(R)-phenyl-4,5-dihydro-pyrazol-1-yl)-propan-1-one, GSK 962, GSK 963 inactive control, GSK 963 negative control, GSK′ 962A, GSK′962A, GSK′963 inactive control, GSK′963 negative control, GSK-962, GSK-962A, GSK962, GSK962A

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About This Item

Empirical Formula (Hill Notation):
C14H18N2O
CAS Number:
Molecular Weight:
230.31
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C(C)(C)C)N1[C@@H](C2=CC=CC=C2)CC=N1

Biochem/physiol Actions

GSK′962 (GSK′962A) corresponds to the inactive (R)-enantiomer of the highly potent and selective RIPK1 (RIP1) inhibitor GSK′963 (GSK′963A). GSK′962 serves as an ideal GSK′963 negative control compound for probing RIPK1-mediated responses both in vitro and in vivo.
Inactive (R)-enantiomer and an ideal negative control of GSK′963 for probing RIPK1-mediated responses both in vitro and in vivo.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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