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SML2908

Sigma-Aldrich

A71915 trifluoroacetate

≥95% (HPLC)

Synonym(s):

(Arg6, β-cyclohexyl-Ala8, D-Tic16, Arg17, Cys18)-Atrial Natriuretic Factor (6-18) amide (Cys7→Cys18 disulfide), TFA salt, A 71915, A-71915, Arg-Cys-β-cyclohexyl-Ala-Gly-Gly-Arg-Ile-Asp-Arg-Ile-D-Tic-Arg-Cys-NH2 (Cys2→Cys13 disulfide), TFA salt, RC-(Cha)-GGRIDRI-(D-Tic)-RC-NH2 (Cys2→Cys13 disulfide, TFA salt, [Arg6, Cha8]ANP-(6-15)-D-Tic-Arg-Cys-NH2 (Cys7→Cys18 disulfide), TFA salt

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CA$32.00

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About This Item

Empirical Formula (Hill Notation):
C69H116N26O15S2 · xC2HF3O2
CAS Number:
Molecular Weight:
1613.95 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77

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Quality Level

Assay

≥95% (HPLC)

form

powder

color

white to off-white

storage temp.

−20°C

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Show Differences

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This Item
HPA048598SAB1300929MABN2268
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

purified immunoglobulin

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

shipped in

ambient

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

12F2.1, monoclonal

Biochem/physiol Actions

A71915 is a potent atrial natriuretic peptide A (ANP, NPPA) receptor (NPR1, ANP-A, ANPR-A, NPR-A) antagonist (pKi = 9.18 (Ki = 650 nM) by competitive binding against 300 nM rat ANP1-28 to human neuroblastoma NB-OK-1 cells; pA2 = 9.45 against rat ANP-induced cGMP production in NB-OK-1 cells). A71915 is reactive toward dog, human, mouse, rabbit, and rat species, and commonly employed both in cultures (1-10 μM) and in vivo for studying NPR-A-mediated responses.
Atrial natriuretic peptide A (ANP, NPPA) receptor (NPR1, ANPRA, NPRA) antagonist with in vitro and in vivo efficacy.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.

    Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.

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