SML2929

Bilastine

≥98% (HPLC)

• Synonym(s): 2-[4-(2-(4-(1-(2-ethoxyethyl)benzimidazole-2-yl)piperidine-1-yl)ethyl)phenyl]-2-methyl-propanoic acid, 4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-α,α-dimethylbenzeneacetic acid, F-96221-BM1
• Empirical Formula (Hill Notation): C₂₈H₃₇N₃O₃
• CAS Number: 202189-78-4
• Molecular Weight: 463.61
• MDL number: MFCD09837814
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [N+H]2(CCC(CC2)c3[n](c4c(n3)cccc4)CCOCC)CCc1ccc(cc1)C(C)(C)C(=O)[O-]
• InChI: 1S/C28H37N3O3/c1-4-34-20-19-31-25-8-6-5-7-24(25)29-26(31)22-14-17-30(18-15-22)16-13-21-9-11-23(12-10-21)28(2,3)27(32)33/h5-12,22H,4,13-20H2,1-3H3,(H,32,33)
• InChI key: ACCMWZWAEFYUGZ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Bilastine is an orally available, potent and selective histamine H1 receptor antagonist that exhibits long drug-target residence time at H1 receptor (73 min), which results in extended H1 receptor antagonism in vitro. Bilastine is used for treatment of allergic rhinitis and urticaria (hives).

orally available, potent and selective histamine H1 receptor antagonist that exhibits long drug-target residence time at H1 receptor

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable