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Key Documents

T0581

Sigma-Aldrich

Transglutaminase from guinea pig liver

≥1.5 units/mg protein, recombinant, expressed in E. coli

Synonym(s):

TGase

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About This Item

EC Number:
UNSPSC Code:
12352204
NACRES:
NA.54

recombinant

expressed in E. coli

Quality Level

specific activity

≥1.5 units/mg protein

shipped in

dry ice

storage temp.

−20°C

Application

10 mM calcium chloride is used for activation of the enzyme.
Transglutaminase has been used in a study to improve quantifiable assays to fully characterize the role of transglutaminase in diseases such as Huntington′s disease and Alzheimer′s disease.Transglutaminase has also been used in a study to develop a nonradioactive dot blot assay for transglutaminase activity.

Unit Definition

One unit will catalyze the formation of 1.0 μmole of hydroxamate per minute from Nα-Z-Gln-Gly and hydroxylamine at pH 6.0 at 37 °C. (L-Glutamic acid γ-monohydroxamate is the standard.)

Physical form

Lyophilized from 10 mM NaH2PO4, 150 mM NaCl, pH 8. Contains maltodextrin.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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