T5699

m-3M3FBS

>97% (HPLC)

• Synonym(s): 2,4,6-Trimethyl-N-(3-trifluoromethyl-phenyl)-benzenesulfonamide, N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide
• Empirical Formula (Hill Notation): C₁₆H₁₆F₃NO₂S
• CAS Number: 200933-14-8
• Molecular Weight: 343.36
• MDL number: MFCD00095824
• UNSPSC Code: 41106300
• PubChem Substance ID: 329826829
• NACRES: NA.77

Properties

• Assay: >97% (HPLC)
• form: powder
• color: white
• mp: 114-114.8 °C (lit.)
• solubility: DMSO: >20 mg/mL
• SMILES string: Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F
• InChI: 1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3
• InChI key: ZIIUUSVHCHPIQD-UHFFFAOYSA-N

Description

Application

m-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis¹. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells².

Biochem/physiol Actions

First known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms).

Preparation Note

m-3M3FBS is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves