T6687

Tris Base

99-101% dry basis, crystalline, meets USP testing specifications

• Synonym(s): 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol, Tris
• Empirical Formula (Hill Notation): C₄H₁₁NO₃
• CAS Number: 77-86-1
• Molecular Weight: 121.14
• EC Number: 201-064-4
• MDL number: MFCD00004679
• UNSPSC Code: 12352104
• PubChem Substance ID: 24900399
• NACRES: NA.25

Properties

• Product Name: Tromethamine, meets USP testing specifications
• Agency: meets USP testing specifications
• Quality Level: 200
• Assay: 99-101% dry basis
• form: crystalline
• pH: 10.0-11.5 (5%)
• SMILES string: NC(CO)(CO)CO
• InChI: 1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
• InChI key: LENZDBCJOHFCAS-UHFFFAOYSA-N

Description

Application

• Preparation and Characterization of a Rifampicin Coamorphous Material with Tromethamine Coformer: An Experimental-Theoretical Study.: This research explores the preparation and characterization of a coamorphous material of rifampicin with Tromethamine, showcasing its potential in enhancing the solubility and stability of pharmaceuticals (Queiroz et al., 2024).


• REKOVER study protocol: a prospective patient treatment registry of tramadol and dexKetoprofen trometamol oral fixed-dose combination (SKUDEXA) in moderate to severe acute pain in real-world setting in Asia.: This study involves the use of dexketoprofen trometamol in a fixed-dose combination with tramadol for managing moderate to severe acute pain, providing evidence of its effectiveness in real-world clinical settings (Ho et al., 2024).

Other Notes

Easily compare specifications for Trizma products with the Trizma specification table.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves