U0750

Uracil

≥99.0%

• Synonym(s): 2,4(1H,3H)-Pyrimidinedione, 2,4-Dihydroxypyrimidine, 2,4-Pyrimidinediol
• Empirical Formula (Hill Notation): C₄H₄N₂O₂
• CAS Number: 66-22-8
• Molecular Weight: 112.09
• Beilstein: 507828
• EC Number: 200-621-9
• MDL number: MFCD00006016
• UNSPSC Code: 41106305
• PubChem Substance ID: 24900618
• NACRES: NA.51

Properties

• biological source: synthetic (organic)
• Quality Level: 300
• Assay: ≥99.0%
• form: powder
• mp: >300 °C (lit.)
• SMILES string: O=C1NC=CC(=O)N1
• InChI: 1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
• InChI key: ISAKRJDGNUQOIC-UHFFFAOYSA-N

Description

General description

Uracil belongs to the pyrimidine nucleobase family. It is naturally occurring and is an important and active part of RNA.

Application

Uracil has been used as:

• a nucleotide standard to determine DNA methylation by high-performance liquid chromatography
• a component of synthetic define medium for culturing Saccharomyces cerevisiae and its strain
• a component of the amino acid supplement to culture Bacillus sp

Biochem/physiol Actions

Uracil and its derivatives play an integral part in medicinal chemistry for the synthesis of cancer, viral infections, autosomal recessive disorder, thyroid, and diabetic drugs.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves