V4512

Vascular Endothelial Growth Factor from mouse

≥98% (SDS-PAGE), recombinant, expressed in E. coli, powder, suitable for cell culture

• Synonym(s): mVEGF, VEGF
• MDL number: MFCD01636149
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• Product Name: Vascular Endothelial Growth Factor from mouse, VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture
• biological source: mouse
• Quality Level: 100
• recombinant: expressed in E. coli
• Assay: ≥98% (SDS-PAGE)
• form: powder
• potency: ≤10 ng/mL
• quality: endotoxin tested
• mol wt: protein 39 kDa
• packaging: pkg of 10 μg; pkg of 50 μg
• storage condition: avoid repeated freeze/thaw cycles
• technique(s): cell culture | mammalian: suitable
• impurities: <1 EU/μg
• UniProt accession no.: Q00731
• storage temp.: −20°C
• Gene Information: mouse ... VEGFA(22339)

Description

General description

Vascular endothelial growth factor is also known as VPF, VEGF and MVCD1. It is secreted from endothelial cells and pericytes in response to hypoxia. It helps in inducing angiogenesis and microvascular hyperpermeability. VEGF levels are associated with vasculitic neuropathy and may be used to predict this disease. It may also act as a marker in the development and progression of early precancerous lesions of oesophagus.

Application

Vascular endothelial growth factor (VEGF) supports development of new blood vessels during embryonic development and after vascular injury.Vascular endothelial growth factor from mouse was used for ELISA and in matrigel plugs (matrigel was supplemented with VEGF).

Other Notes

Homodimeric protein consisting of two 165 amino acid polypeptide chains of mouse VEGF.

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Physical form

Lyophilized from a 0.2 μm filtered buffered solution.

Analysis Note

The biological activity is measured by the ability to stimulate ³H-thymidine incorporation in human umbilical vein endothelial cells (HUVEC) and bovine aortic endothelial cells.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves