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Merck

CLDN6

claudin 6

Sinonimi:
Specie:
ID UniProtKB:
ID gene:
  • Human(9074) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
  • Mouse(54419) claudin 6
  • Rat(287098) claudin 6
  • dog(490048) claudin 6
  • cow(511318) claudin 6
  • domestic cat(101100433) claudin 6
  • naked mole-rat(101723329) claudin 6
  • domestic guinea pig(100735319) claudin 6
  • sheep(101117294) claudin 6

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Antibodies

Product Number
Descrizione
Reattività con
Applicazione
Monoclonal Anti-CLDN6 antibody produced in mouse, clone 4H4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Monoclonal Anti-CLDN6 antibody produced in mouse, clone 1P8, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Anti-Claudin-6 Antibody, clone 2, ,
Reattività con
human
Applicazione
flow cytometry
immunocytochemistry

immunohistochemistry

inhibition assay

western blot
Anti-phospho-Claudin 6 (pTyr219) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-CLDN6 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rabbit
Applicazione
western blot

esiRNA

Product Number
Descrizione
Specie
MISSION® esiRNA, targeting mouse Cldn6,
Specie
mouse
MISSION® esiRNA, targeting human CLDN6,
Specie
human