116203

2-Chloro-3-hydroxypyridine

98%

• Synonym(s): 2-Chloro-3-pyridinol
• Empirical Formula (Hill Notation): C₅H₄ClNO
• CAS Number: 6636-78-8
• Molecular Weight: 129.54
• EC Number: 229-635-3
• MDL number: MFCD00006235
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847271
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• mp: 170-172 °C (lit.)
• SMILES string: Oc1cccnc1Cl
• InChI: 1S/C5H4ClNO/c6-5-4(8)2-1-3-7-5/h1-3,8H
• InChI key: RSOPTYAZDFSMTN-UHFFFAOYSA-N

Description

Application

2-Chloro-3-hydroxypyridine has been used in the preparation of 3-hydroxypyridine-2( 1 H)-selone. It has also been used in the synthesis of all four possible benzo[4,5]furopyridine tricyclic heterocycles: benzo[4,5]furo[2,3-b]pyridine, benzo[4,5]furo[2,3-c]pyridine, benzo[4,5]furo[3,2-c]pyridine, and benzo[4,5]furo[3,2-b]pyridine. the synthesis involves α and γ-activation of chloropyridines, as well as palladium-mediated reactions.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves