255858

Bromonitromethane

technical grade, 90%

• Synonym(s): α-Bromonitromethane, Nitrobromomethane
• Linear Formula: BrCH₂NO₂
• CAS Number: 563-70-2
• Molecular Weight: 139.94
• EC Number: 209-258-0
• MDL number: MFCD00007401
• UNSPSC Code: 12352100
• PubChem Substance ID: 24855488
• NACRES: NA.22

Properties

• grade: technical grade
• Quality Level: 100
• Assay: 90%
• form: liquid
• refractive index: n20/D 1.496 (lit.)
• bp: 146-148 °C/750 mmHg (lit.)
• density: 2.007 g/mL at 25 °C (lit.)
• functional group: amine; bromo; nitro
• SMILES string: [O-][N+](=O)CBr
• InChI: 1S/CH2BrNO2/c2-1-3(4)5/h1H2
• InChI key: DNPRVXJGNANVCZ-UHFFFAOYSA-N

Description

Application

Bromonitromethane has been used:

• in production of various protected α-bromo nitroalkane donors (including Fmoc) for use in Umpolung amide synthesis
• in preparation of (Z)-1-bromo-1-nitroalkenes via sodium iodide-catalyzed Henry reaction
• in diastereo- and enantioselective cyclopropanation of β,γ-unsaturated a-ketoesters via domino Michael-addition/intramolecular-alkylation strategy

Safety Information

• Pictograms: GHS03,GHS07
• Signal Word: Danger
• Hazard Statements: H272,H315,H319,H335
• Precautionary Statements: P210 - P220 - P261 - P264 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Ox. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 5.1B - Oxidizing hazardous materials
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves