512362

3-Methylpyridine-2-carboxylic acid

97%

• Synonym(s): 3-Methylpicolinic acid
• Empirical Formula (Hill Notation): C₇H₇NO₂
• CAS Number: 4021-07-2
• Molecular Weight: 137.14
• MDL number: MFCD00191553
• UNSPSC Code: 12352100
• PubChem Substance ID: 24873626
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: solid
• mp: 114-118 °C
• functional group: carboxylic acid
• SMILES string: Cc1cccnc1C(O)=O
• InChI: 1S/C7H7NO2/c1-5-3-2-4-8-6(5)7(9)10/h2-4H,1H3,(H,9,10)
• InChI key: LMHIBYREWJHKNZ-UHFFFAOYSA-N

Description

General description

3-Methylpyridine-2-carboxylic acid, also known as 3-methylpicolinic acid (3-MepicH), is a 3-substituted picolinic acid. The dianion formed by reacting 3-MepicH with lithium diisopropylamide (LDA) can undergo C-alkylation with 3-chlorobenzyl chloride.

Application

3-Methylpyridine-2-carboxylic acid (3-MepicH) may be used as a ligand in the synthesis of the following metal complexes:

• [Cu(3-Mepic)₂(4-pic)] where 4-pic=4-picoline and [Cu(3-Mepic)₂]·2H₂O
• [Co(3-Mepic)₃]
• [Ni(3-Mepic)₂(H₂O)₂]
• bis(3-methyl-picolinato-κ² N,O)(1,10-phenanthroline)zinc(II) tetrahydrate

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves