902047

Pyridine-2,6-bis(carboximidamide) dihydrochloride

≥95%

• Synonym(s): Weix 2-pyridylcarboxamidine ligand for nickel catalysis
• Empirical Formula (Hill Notation): C₇H₁₁Cl₂N₅
• CAS Number: 1394382-56-9
• Molecular Weight: 236.10
• MDL number: MFCD31718854
• UNSPSC Code: 12352101
• NACRES: NA.22

Properties

• Assay: ≥95%
• form: powder or crystals
• reaction suitability: core: nickel; reaction type: Cross Couplings; reagent type: catalyst
• SMILES string: Cl.Cl.NC(=N)c1nc(ccc1)C(=N)N
• InChI: 1S/C7H9N5.2ClH/c8-6(9)4-2-1-3-5(12-4)7(10)11;;/h1-3H,(H3,8,9)(H3,10,11);2*1H
• InChI key: YLMVDWSPWFNTRJ-UHFFFAOYSA-N

Description

Application

This pyridyl carboxamidine ligand has been demonstrated by Daniel Weix′s lab to enable nickel-catalyzed cross-coupling of diverse basic nitrogen heterocycles with primary and secondary alkyl halides.

Other Notes

Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling

Electrochemical Nickel Catalysis for Sp²-Sp³ Cross-Electrophile Coupling Reactions of Unactivated Alkyl Halides

New ligands for nickel catalysis from diverse pharmaceutical heterocycle libraries

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable