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840038P

Avanti

12:0 PS

1,2-dilauroyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

Synonym(s):

1,2-didodecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DLPS; PS(12:0/12:0)

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About This Item

Empirical Formula (Hill Notation):
C30H57NO10PNa
CAS Number:
Molecular Weight:
645.74
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840038P-10mg)
pkg of 1 × 200 mg (840038P-200mg)
pkg of 1 × 25 mg (840038P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 840038P

lipid type

phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]

InChI

1S/C30H58NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-28(32)38-23-26(24-39-42(36,37)40-25-27(31)30(34)35)41-29(33)22-20-18-16-14-12-10-8-6-4-2;/h26-27H,3-25,31H2,1-2H3,(H,34,35)(H,36,37);/q;+1/p-1/t26-,27+;/m1./s1

InChI key

QBSSGICBQYAHPS-OUPRKWGVSA-M

General description

Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.

Application

12:0 PS may be used:
  • in the preparation of large unilamellar vesicles (LUVs)
  • as a standard to spike replicas of extracted lipid droplets and calibration curve generation for lipidomic analysis
  • to study its effects on α-secretase activity

Biochem/physiol Actions

Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.

Packaging

5 mL Amber Glass Screw Cap Vial (840038P-10mg)
5 mL Amber Glass Screw Cap Vial (840038P-200mg)
5 mL Amber Glass Screw Cap Vial (840038P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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