M3074

MMPIP

≥98% (HPLC)

• Synonym(s): 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[ 4,5-c]pyridin-4(5H)-one
• Empirical Formula (Hill Notation): C₁₉H₁₅N₃O₃
• CAS Number: 479077-02-6
• Molecular Weight: 333.34
• MDL number: MFCD12195836
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817961
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to off-white
• solubility: DMSO: ≥10 mg/mL
• originator: Merck & Co., Inc., Kenilworth, NJ, U.S.
• storage temp.: room temp
• SMILES string: COc1ccc(cc1)C2=Cc3onc(-c4ccncc4)c3C(=O)N2C
• InChI: 1S/C19H15N3O3/c1-22-15(12-3-5-14(24-2)6-4-12)11-16-17(19(22)23)18(21-25-16)13-7-9-20-10-8-13/h3-11H,1-2H3
• InChI key: PDWYBOZNEVALOV-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7).

MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). It also displays intrinsic activity and acts as an inverse agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable