R2027

Ral B human

recombinant, expressed in E. coli, buffered aqueous glycerol solution

• MDL number: MFCD03792555
• UNSPSC Code: 12352202
• NACRES: NA.56

Properties

• recombinant: expressed in E. coli
• Quality Level: 200
• form: buffered aqueous glycerol solution
• UniProt accession no.: P11234
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... RALB(5899)

Description

Application

Can be used as a control in immunoblotting and in protein binding assays.

Biochem/physiol Actions

Ral B (21 kDa, native), a member of the Ras-like GTP binding protein family, is a crucial link in intracellular signaling cascades.

Ral B has been implicated in invasion and metastasis of human cancer cells. Reports have shown that depletion of Ral B by siRNA results in significantly reduced migration rates of tumor cells, while constitutively active Ral B promoted migration.

Other Notes

GST-tagged Ras-like fusion protein

Physical form

Supplied as a solution in 50 mM Tris, pH 7.5, containing 150 mM sodium chloride, 10 mM magnesium chloride, 1 mM DTT, and 10% glycerol.

Safety Information

• Storage Class Code: 10 - Combustible liquids