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S7448

Sigma-Aldrich

STF-62247

≥98% (HPLC), solid

Synonym(s):

N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine

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About This Item

Empirical Formula (Hill Notation):
C15H13N3S
CAS Number:
315702-99-9
Molecular Weight:
267.35
MDL number:
MFCD01121974
UNSPSC Code:
12352200
PubChem Substance ID:
329824583
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

solid

solubility

DMSO: soluble 26 mg/mL
H2O: insoluble

storage temp.

room temp

SMILES string

Cc1cccc(Nc2nc(cs2)-c3ccncc3)c1

InChI

1S/C15H13N3S/c1-11-3-2-4-13(9-11)17-15-18-14(10-19-15)12-5-7-16-8-6-12/h2-10H,1H3,(H,17,18)

InChI key

KATNUHQNJGNLPW-UHFFFAOYSA-N

Application

STF-62247 may be used as positive control in autophagy inducing cell signaling studies.

Biochem/physiol Actions

STF-62247 induces the formation of large vacuoles in the von Hippel-Lindau deficient renal carcinoma cells, a characteristic of autophagy.1
STF-62247 is a selective inducer of autophagy in VHL-deficient renal cell carcinoma cells.

Hazard Statements

H413

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
032M4745V
030M4741
108K4708

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