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SAB1300729

Sigma-Aldrich

Anti-Phospho-INSR-pY1185 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-CD220 antigen, Anti-INSR, Anti-IR, Anti-Insulin receptor [Precursor]

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₹44,440.00
100 G
₹130,955.00

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25 G
₹44,440.00
100 G
₹130,955.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

₹44,440.00

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

dot blot: suitable
indirect ELISA: 1:1000

NCBI accession no.

NP_000199

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This Item
3993968.01776B8703
Benzoin 98%

B8681

Benzoin

Benzoin purified by sublimation, ≥99.5%

399396

Benzoin

Benzoin for synthesis

8.01776

Benzoin

Benzoin methyl ether 96%

B8703

Benzoin methyl ether

assay

98%

assay

≥99.5%

assay

≥99.0% (GC)

assay

96%

bp

194 °C/12 mmHg (lit.)

bp

194 °C/12 mmHg (lit.)

bp

344 °C/1023 hPa

bp

-

form

powder

form

powder

form

crystals

form

crystals

mp

134-138 °C (lit.)

mp

134-138 °C (lit.)

mp

132-134 °C

mp

47.5-48.5 °C (lit.)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

Gene Information

human ... ACHE(43), BCHE(590), CES1(1066)

Gene Information

human ... ACHE(43), BCHE(590), CES1(1066)

Gene Information

-

Gene Information

-

General description

Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3′-kinase (PI3K). This protein can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked.

Immunogen

INSR (NP_000199, 1167-1202)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1185 of human INSR.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Lot/Batch Number
    010M1763

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