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SAB5700789

Sigma-Aldrich

Anti-E-Cadherin antibody produced in rabbit

Synonym(s):

Arc-1, CD324, CDH1, CDHE, E-Cadherin, ECAD, LCAM, UVO

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1 KIT
MYR 5,216.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

MYR 5,216.00

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biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

90
 97

species reactivity

mouse, human, rat

concentration

1.19 mg/ml

technique(s)

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

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Anti-E-Cadherin antibody produced in rabbit

SAB5700789

Anti-E-Cadherin antibody produced in rabbit

Anti-E-cadherin antibody produced in rabbit affinity isolated antibody

SAB4503751

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Anti-CDH1 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

HPA004812

Anti-CDH1 antibody produced in rabbit

Anti-N Cadherin antibody produced in rabbit

SAB5700190

Anti-N Cadherin antibody produced in rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

form

buffered aqueous solution

species reactivity

mouse, human, rat

species reactivity

human

species reactivity

human

species reactivity

human, mouse, rat

UniProt accession no.

P12830

UniProt accession no.

P12830

UniProt accession no.

P12830

UniProt accession no.

P19022

General description

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 373-622 of human E-Cadherin (NP_004351.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Geoffrey M Lynn et al.
    Nature biotechnology, 33(11), 1201-1210 (2015-10-27)
    The efficacy of vaccine adjuvants such as Toll-like receptor agonists (TLRa) can be improved through formulation and delivery approaches. Here, we attached small molecule TLR-7/8a to polymer scaffolds (polymer-TLR-7/8a) and evaluated how different physicochemical properties of the TLR-7/8a and polymer
    Jin-Gyoung Jung et al.
    PLoS genetics, 10(10), e1004751-e1004751 (2014-10-31)
    The Notch3 signaling pathway is thought to play a critical role in cancer development, as evidenced by the Notch3 amplification and rearrangement observed in human cancers. However, the molecular mechanism by which Notch3 signaling contributes to tumorigenesis is largely unknown.
    Diana Romero et al.
    Carcinogenesis, 37(1), 18-29 (2015-10-28)
    Dickkopf-3 (Dkk-3) is a secreted protein whose expression is downregulated in many types of cancer. Endogenous Dkk-3 is required for formation of acini in 3D cultures of prostate epithelial cells, where it inhibits transforming growth factor (TGF)-β/Smad signaling. Here, we
    Alexander C Cerny et al.
    PLoS genetics, 11(10), e1005578-e1005578 (2015-10-29)
    Recycling of signaling proteins is a common phenomenon in diverse signaling pathways. In photoreceptors of Drosophila, light absorption by rhodopsin triggers a phospholipase Cβ-mediated opening of the ion channels transient receptor potential (TRP) and TRP-like (TRPL) and generates the visual

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