Skip to Content
Merck

Key Documents

View All Documentation

Skip To

SAB5702265

Sigma-Aldrich

[KO Validated]Anti-AKT1 Antibody, clone 0O8L9, Rabbit Monoclonal

Synonym(s):

AKT,CWS6,PKB,PKB-ALPHA,PRKBA,RAC,RAC-ALPHA,AKT1

Sign Into View Organizational & Contract Pricing

Select a Size

6 EA
MYR 435.00

MYR 435.00

Check Cart for Availability

Select a Size

Change View
6 EA
MYR 435.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

MYR 435.00

Check Cart for Availability
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

Quality Level

100

material

colorless

clone

0O8L9, monoclonal

form

liquid

mol wt

60 kDa

species reactivity

rat, rat, human

concentration

1 mg/mL

technique(s)

western blot: 1:500 - 1:1000

color

colorless

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
W357405W438700W385409
4-Ethyloctanoic acid ≥98%, FG

W380008

4-Ethyloctanoic acid

4-Methylnonanoic acid ≥97%, FG

W357405

4-Methylnonanoic acid

2-Pentylthiophene ≥98%, FG

W438700

2-Pentylthiophene

3-Mercapto-3-methylbutan-1-ol ≥98%, FG

W385409

3-Mercapto-3-methylbutan-1-ol

organoleptic

meaty

organoleptic

meaty

organoleptic

fatty; meaty

organoleptic

meaty

grade

FG, Kosher, Halal

grade

FG, Halal, Kosher

grade

FG, Halal, Kosher

grade

FG, Kosher

biological source

synthetic

biological source

synthetic

biological source

synthetic

biological source

synthetic

food allergen

no known allergens

food allergen

no known allergens

food allergen

no known allergens

food allergen

no known allergens

assay

≥98%

assay

≥97%

assay

≥98%

assay

≥98%

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

General description

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 381-480 of human AKT1 (NP_005154.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

    If you need assistance, please contact Customer Support

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    The percutaneous absorption of triarylmethane and phenoxazine type colour former components of carbonless copy papers.
    B D Cameron et al.
    The Annals of occupational hygiene, 30(1), 115-122 (1986-01-01)
    Dermatitis from crystal violet.
    P N Whitehead
    Contact dermatitis, 19(2), 141-142 (1988-08-01)
    Uli Schmidhammer et al.
    The journal of physical chemistry. A, 112(37), 8487-8496 (2008-08-22)
    The intramolecular electron-transfer reaction in crystal violet lactone in polar aprotic solvents is studied with femtosecond transient absorption spectroscopy. The initially excited charge transfer state (1)CT A is rapidly converted into a highly polar charge transfer state (1)CT B. This
    Allergic contact dermatitis to crystal violet lactone [corrected] in carbonless copy paper.
    S A Shehade et al.
    Contact dermatitis, 17(5), 310-311 (1987-11-01)
    Kunihiro Ichimura et al.
    Langmuir : the ACS journal of surfaces and colloids, 24(13), 6470-6479 (2008-06-10)
    The solid phase adsorption of crystal violet lactone (CVL) on five types of Stober silica nanopowders with BET specific surface areas in the range of 50-800 m2/g under dry milling conditions was described for the first time. The hydrogen bonding
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service