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Key Documents

SML0926

Sigma-Aldrich

ML314 maleate

≥98% (HPLC)

Synonym(s):

2-Cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)-piperazin-1-yl)quinazoline maleate

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About This Item

Empirical Formula (Hill Notation):
C24H28N4O3 · C4H4O4
Molecular Weight:
536.58
UNSPSC Code:
12352202
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

Biochem/physiol Actions

ML314 is a biased agonist of the Neruotensin 1 (NTR1) receptor. ML314 induces recruitment of β-arrestin to NTR1 with an EC50 of 2 μM, but does not induce G-protein mediated Ca2+ mobilization.
ML314 is a neurotensin receptor (NTR1) receptor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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