T5771
Testosterone 3-(O-carboxymethyl)oxime: BSA - fluorescein isothiocyanate conjugate
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About This Item
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Assay
≥98.00% (TLC)
Quality Level
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
extent of labeling
~3 mol FITC per mol BSA
~10 mol steroid per mol BSA
technique(s)
flow cytometry: suitable
solubility
water: 1.90-2.10 mg/mL, clear to faintly hazy, orange
shipped in
ambient
storage temp.
2-8°C
Application
Testosterone 3-(O-carboxymethyl)oxime: BSA-FITC has been used for flow cytometric assays in serum-free cell cultures2. It has also been used for fluorescence labeling experiments in L6 cells3.
Biochem/physiol Actions
Studies have reported that BSA-coupled testosterone can block the growth of LNCaP cells. Furthermore, it can activate Fas protein and cell death, as well as reduce the translocation, adhesion and incursion of iAR-negative, DU145 prostate cancer cells2.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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