1297001

Human chorionic gonadotropin

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Chorionic gonadotropin human, Choriogonin, HCG
• CAS Number: 9002-61-3
• MDL number: MFCD00130797
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: gonadotropin
• form: solid
• mol wt: 37.9 kDa
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C

Description

General description

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by the placenta, used therapeutically for reproductive hormone regulation. The USP reference standard supports potency assays, identity testing, and bioassay calibration for hCG drug substances.

The USP biologics proteins category provides critical standards and reference materials necessary for the development and manufacturing of therapeutic proteins. These proteins, which can be naturally derived or genetically engineered, are essential in treating various diseases and conditions, ensuring that they meet quality, safety, and efficacy standards.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.

Packaging

1 vial, 530 USP units per package

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

This product is part of the USP Biologics program.

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H361
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable