1304107

Heparin Sodium Molecular Weight Calibrant

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Heparin sodium salt solution
• CAS Number: 9041-08-1
• MDL number: MFCD00081689
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: heparin
• form: powder
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: [Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
• InChI: 1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-
• InChI key: JRTRSJGZMRQDHI-UHFFFAOYSA-N

Description

General description

This molecular weight calibrant standard is essential for the determination of heparin′s molecular weight distribution via size exclusion chromatography. Accurate molecular profiling ensures the safety and efficacy of heparin products and supports regulatory submission data.

The USP biologics carbohydrates category includes a variety of carbohydrate-based substances that are essential in the development and manufacturing of therapeutic products. These carbohydrates play crucial roles in biological processes and are often utilized as excipients, stabilizers, or active ingredients in pharmaceuticals. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of carbohydrate therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Heparin Sodium is a mixture of sulfated glycosaminoglycans in the form of sodium salt. It is composed of heterogeneous molecules with different molecular weights, collectively exhibiting multiple activities that affect various factors involved in the blood clotting process. This substance naturally occurs in mammalian tissues and is typically derived from sources such as the intestinal mucosa or other applicable tissues obtained from domestic mammals commonly consumed as food by humans. Heparin Sodium Molecular Weight Calibrant USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Heparin Sodium Molecular Weight Calibrant USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Heparin Sodium

Other Notes

Heparin Sodium is a mixture of sulfated glycosaminoglycans in the form of sodium salt. It is composed of heterogeneous molecules with different molecular weights, collectively exhibiting multiple activities that affect various factors involved in the bloo

Heparin Sodium is a mixture of sulfated glycosaminoglycans in the form of sodium salt. It is composed of heterogeneous molecules with different molecular weights, collectively exhibiting multiple activities that affect various factors involved in the blood clotting process. This substance naturally occurs in mammalian tissues and is typically derived from sources such as the intestinal mucosa or other applicable tissues obtained from domestic mammals commonly consumed as food by humans. Heparin Sodium Molecular Weight Calibrant USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

This product is part of the USP Biologics program.

Sales restrictions may apply.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable