1709007

Vancomycin hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Vancomycin monohydrochloride
• Empirical Formula (Hill Notation): C₆₆H₇₅Cl₂N₉O₂₄ · HCl
• Molecular Weight: 1485.71
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: vancomycin
• form: solid
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C

Description

General description

Vancomycin hydrochloride is a glycopeptide antibiotic effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It inhibits cell wall biosynthesis by binding to D-Ala-D-Ala termini of cell wall precursors. The USP standard provides a validated benchmark for microbiological assays and chromatographic identification techniques.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Vancomycin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Vancomycin Hydrochloride Capsules
• Vancomycin Hydrochloride for Injection
• Vancomycin Hydrochloride for Oral Solution
• Vancomycin Injection
• Vancomycin

Packaging

4 vials, each vial contains 99,300 mcg of vancomycin activity

Other Notes

This product is part of the USP Biologics program.

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317,H334
• Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable