165336

Methylboronic acid

97%

• 동의어(들): Methaneboronic acid
• Linear Formula: CH₃B(OH)₂
• CAS Number: 13061-96-6
• Molecular Weight: 59.86
• Beilstein: 1731087
• MDL number: MFCD00002105
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24850133
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 97%
• 양식: solid
• mp: 91-94 °C (lit.)
• SMILES string: CB(O)O
• InChI: 1S/CH5BO2/c1-2(3)4/h3-4H,1H3
• InChI key: KTMKRRPZPWUYKK-UHFFFAOYSA-N

설명

애플리케이션

Methylboronic acid can be used as a reagent:

• In the palladium-catalyzed Stille and Suzuki-Miyaura cross-couplings.
• In the microwave-heated heterogeneous palladium (Pd)-catalytized reactions.
• In ruthenium (Ru)-catalyzed silylation reactions
• To prepare bis(aminotropone) titanium (Ti) catalysts for ethylene polymerizations.
• In the enantioselective asymmetric bromoaminocyclization and bromoaminocyclization using amino-thiocarbamate catalysts.
• To prepare common building blocks for pharmaceuticals and agrochemicals.
• To prepare chrysin analogs by Suzuki-Miyaura coupling reactions.
• To prepare casein kinase I inhibitors.
• In the divergent C-H functionalizations directed by sulfonamide pharmacophores in drug discovery.
• In the synthesis of unsymmetrical monosulfides from disulfides via copper-catalyzed coupling with boronic acids.
• In a palladium-catalyzed coupling with enol tosylates.
• For derivatizing many carbohydrates and biologically active compounds for GLC analysis.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves