219142

5-Bromopyrimidine

97%

• 실험식(Hill 표기법): C₄H₃BrN₂
• CAS Number: 4595-59-9
• Molecular Weight: 158.98
• Beilstein: 107326
• EC Number: 224-992-1
• MDL number: MFCD00006117
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24853108
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 97%
• 양식: solid
• mp: 67-73 °C (lit.)
• 작용기: bromo
• SMILES string: Brc1cncnc1
• InChI: 1S/C4H3BrN2/c5-4-1-6-3-7-2-4/h1-3H
• InChI key: GYCPLYCTMDTEPU-UHFFFAOYSA-N

설명

일반 설명

Rapid nucleophilic displacement reactions of 5-bromopyrimidine with nucleophiles under microwave irradiation has been studied. 5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine.

애플리케이션

5-Bromopyrimidine was used in the synthesis of:

• N-heteroaryl substituted 9-arylcarbazolyl derivatives via palladium-catalyzed aerobic and ligand-free Suzuki reaction
• (5-(phenylethynyl)pyrimidine) via microwave assisted organic synthesis (MAOS) Sonogashira protocol

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves